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Food Science and Technology International
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Revisión: Implicaciones toxicológicas y nutricionales de la toxina T-2 / Review: Toxicological and nutritional implications of T-2 toxin

M. Leal

Facultad de Estudios Superiores Cuautitlán. Universidad Nacional Autónoma de México. Apartado Postal 2-29, Querétaro, Qro. 76020 México

E. González de Mejía

Universidad Autónoma de Querétaro. Facultad de Química. Centro Universitario. Cerro de las Campanas. Querétaro, Qro. 76049 México

Trichothecenes are mycotoxins produced by species of the genus Fusarium. These toxins are associated with health problems in humans and animals. The most common trichothecenes in cereals are deoxynivalenol, HT-2 toxin, diacetoxyscirpenol, nivalenol, neosolaniol and T-2 toxin; the latter is the most widely studied because it is easy to produce in the laboratory. The effects of T-2 toxicosis include dermatonecrosis, reduced body weight and efficiency of food utilization, severe diarrhoea, haemorrhage, necrosis of the upper alimentary tract, anaemia, immuno suppression ; and in birds, poor feathering. This paper reviews the latest information about the occurrence, chemical characteristics, toxicity, metabolic alterations, biotransformation and detoxifi cation methods of the T-2 toxin.

Key Words: T-2 toxin • trichothecenes • mycotoxins • nutrition • biotransformation • detoxification

Food Science and Technology International, Vol. 3, No. 4, 241-250 (1997)
DOI: 10.1177/108201329700300402
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